Compile Data Set for Download or QSAR
Found 72 of ec50 for CDK8/Cyclin C
having polymerids = 3907,50007067 and
complexids = 50004167
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248686(CHEMBL4071040)copy SMILEScopy InChI
Affinity DataEC50:  0.350nMAssay Description:Binding affinity towards HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248656(CHEMBL4086487)copy SMILEScopy InChI
Affinity DataEC50:  0.400nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248645(CHEMBL4061525)copy SMILEScopy InChI
Affinity DataEC50:  0.580nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248633(CHEMBL4083552)copy SMILEScopy InChI
Affinity DataEC50:  0.770nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248614(CHEMBL4066819)copy SMILEScopy InChI
Affinity DataEC50:  1.30nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248611(CHEMBL4060856)copy SMILEScopy InChI
Affinity DataEC50:  1.40nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248615(CHEMBL4077627)copy SMILEScopy InChI
Affinity DataEC50:  1.5nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248635(CHEMBL4070408)copy SMILEScopy InChI
Affinity DataEC50:  2nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248640(CHEMBL4074204)copy SMILEScopy InChI
Affinity DataEC50:  2.30nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241885(CHEMBL4060759)copy SMILEScopy InChI
Affinity DataEC50:  2.30nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241892(CHEMBL4072106)copy SMILEScopy InChI
Affinity DataEC50:  2.40nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248612(CHEMBL4076395)copy SMILEScopy InChI
Affinity DataEC50:  2.60nMAssay Description:Binding affinity towards HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248638(CHEMBL4062244)copy SMILEScopy InChI
Affinity DataEC50:  3nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248662(CHEMBL4091345)copy SMILEScopy InChI
Affinity DataEC50:  3nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241859(CHEMBL4063908)copy SMILEScopy InChI
Affinity DataEC50:  3.10nMAssay Description:Inhibition of [3H]mazindol binding to Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241896(CHEMBL4081088)copy SMILEScopy InChI
Affinity DataEC50:  3.60nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241860(CHEMBL4079977)copy SMILEScopy InChI
Affinity DataEC50:  5.5nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241863(CHEMBL4060561)copy SMILEScopy InChI
Affinity DataEC50:  7nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248687(CHEMBL4090775)copy SMILEScopy InChI
Affinity DataEC50:  7.40nMAssay Description:Binding affinity towards HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248609(CHEMBL4088931)copy SMILEScopy InChI
Affinity DataEC50:  8.30nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241864(CHEMBL4069244)copy SMILEScopy InChI
Affinity DataEC50:  8.40nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241862(CHEMBL4059523)copy SMILEScopy InChI
Affinity DataEC50:  8.40nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248690(CHEMBL4082469)copy SMILEScopy InChI
Affinity DataEC50:  8.90nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248632(CHEMBL4069854)copy SMILEScopy InChI
Affinity DataEC50:  9.10nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241879(CHEMBL4082587)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241881(CHEMBL4063489)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241868(CHEMBL4092865)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241871(CHEMBL4087219)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241866(CHEMBL4063709)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241891(CHEMBL4082444)copy SMILEScopy InChI
Affinity DataEC50:  14nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248658(CHEMBL4060714)copy SMILEScopy InChI
Affinity DataEC50:  16nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241857(CHEMBL4091382)copy SMILEScopy InChI
Affinity DataEC50:  16nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241858(CHEMBL4070459)copy SMILEScopy InChI
Affinity DataEC50:  17nMAssay Description:Inhibition of [3H]WIN-35428l binding to Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241890(CHEMBL4098004)copy SMILEScopy InChI
Affinity DataEC50:  17nMAssay Description:Inhibition of [3H]paroxetine binding to Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241900(CHEMBL4066959)copy SMILEScopy InChI
Affinity DataEC50:  19nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241875(CHEMBL4091527)copy SMILEScopy InChI
Affinity DataEC50:  21nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248613(CHEMBL4063680)copy SMILEScopy InChI
Affinity DataEC50:  21nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50593061(CHEMBL5183704)copy SMILES
Affinity DataEC50:  24nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2DX9PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248608(CHEMBL4063358)copy SMILEScopy InChI
Affinity DataEC50:  25nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241897(CHEMBL4061835)copy SMILEScopy InChI
Affinity DataEC50:  27nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248639(CHEMBL4072372)copy SMILEScopy InChI
Affinity DataEC50:  28nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241882(CHEMBL4101552)copy SMILEScopy InChI
Affinity DataEC50:  28nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248634(CHEMBL4061783)copy SMILEScopy InChI
Affinity DataEC50:  66nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50248705(CHEMBL4102907)copy SMILEScopy InChI
Affinity DataEC50:  70nMAssay Description:Inhibition of CDK8 in human SW620 cells assessed as decrease in STAT1 phosphorylation at Ser727 after 2 hrs by Western blot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9D6HPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241861(CHEMBL4087859)copy SMILEScopy InChI
Affinity DataEC50:  84nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241895(CHEMBL4074871)copy SMILEScopy InChI
Affinity DataEC50:  95nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241872(CHEMBL4097361)copy SMILEScopy InChI
Affinity DataEC50:  97nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241889(CHEMBL4083599)copy SMILEScopy InChI
Affinity DataEC50:  110nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241870(CHEMBL4094902)copy SMILEScopy InChI
Affinity DataEC50:  110nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
Takeda Pharmaceutical Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50241869(CHEMBL4093832)copy SMILEScopy InChI
Affinity DataEC50:  130nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59XWPubMed
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